Lake Nona is Orlando's medical city and innovation hub. Vacant land here is extremely limited and priced accordingly. Nearby alternatives exist in St. Cloud and Narcoossee.
Lake Nona is southeast Orlando's master-planned innovation district. Developed primarily by Tavistock Development Company, it has grown into one of the most recognized communities in Central Florida. The area is home to the Orlando VA Medical Center, Nemours Children's Hospital, the USTA National Campus, and a growing cluster of tech and life sciences companies. The combination of world-class healthcare, education, and lifestyle amenities has made Lake Nona one of the highest-value real estate markets in the Orlando metro.
The challenge for land buyers is simple: very little raw land remains. Most of the developable acreage in Lake Nona proper has already been absorbed by Tavistock or sold to homebuilders and commercial developers. What does come to market tends to be small infill lots at premium prices. Buyers looking for acreage of an acre or more near Lake Nona typically end up searching south into St. Cloud or east along the Narcoossee Road corridor, where larger parcels still exist at more accessible price points.
If you are set on living within a short drive of Lake Nona but need more land than a standard subdivision lot, the areas around Boggy Creek Road, Narcoossee, and northern St. Cloud offer the closest alternatives. The Narcoossee corridor connects directly to Lake Nona in about 15 minutes, making it a practical option for buyers who want acreage without giving up access to Lake Nona's amenities.
2.5 acres in the heart of Orlando near the Florida Mall corridor. Price recently reduced.
Looking for more land near Lake Nona? Vacant acreage in Lake Nona proper is almost nonexistent in 2026. Most available land has been absorbed by master-plan developers. For parcels within 15 to 20 minutes of Lake Nona, check our St. Cloud listings and Kissimmee listings, where inventory is deeper and prices are more accessible.
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Lake Nona represents some of the highest land values in the Orlando metro, and the limited supply of vacant parcels makes this one of the most competitive markets in Central Florida. Most buyers who want acreage near Lake Nona end up exploring the Narcoossee corridor, northern St. Cloud, or the Boggy Creek Road area for larger parcels at more manageable prices.
OrlandoAcreage.com tracks land availability across the entire Orlando metro. If you need help navigating the Lake Nona market or finding alternatives nearby, reach out to a land specialist who knows the area.